The Question of the Missing Head, by E. J. Copperman and Jeff Cohen

Samuel Hoenig has Asperberger's Syndrome which he believes gives him a unique set of skills for answering questions.  So when he is asked what happened to the frozen head missing from the Garden State Cryonics Institute he has no choice but to find out.  Aided, particularly in navigating social niceties, by his colleague Janet Washburn, Samuel's powers of deduction lead him to a killer.